Publications from NDSU

2007

"Synthesis and Evaluation of Novel Heterocyclic MMP Inhibitors"
Ryuji Hayash, Xiaomin Jin and Gregory R. Cook*
Bioorg. Med. Chem. Lett. 2007, in press, http://dx.doi.org/10.1016/j.bmcl.2007.10.020.

"Intermolecular Friedel-Crafts Reaction Catalyzed by InCl3"
Miho Kaneko, Ryuji Hayashi and Gregory R. Cook*
Tetrahedron Letters, 2007, 48, 7085.

“Readily Accessible, Modular and Tuneable BINOL 3,3'-Perfluoroalkylsulfones: Highly Efficient Catalysts for Enantioselective In-Mediated Imine Allylation”
Robert Kargbo, Yoko Takahashi, Santosh Bhor, Gregory R. Cook*, Guy C. Lloyd-Jones*, Ian R. Shepperson,
J. Am. Chem. Soc. 2007, 129, 3846 .

"Remarkably Mild and Efficient Intramolecular Friedel-Crafts Cyclization Catalyzed by In(III)”
Hayashi, R.; Cook, G. R.
Org. Lett. 2007, 9, 1311 .

“Drug-membrane Interactions Studied in Phospholipid Monolayers Adsorbed on Non-porous Alkylated Microspheres”
Lukacova, V.; Peng, M.; Fanucci, G.; Tandlich, R.; Hinderliter, A.; Maity, B. Manivannan, E.; Cook, Gregory R.; Balaz, S.
J. Biomolecular Screening 2007, 12, 186-202.

"Stereoselective Indium-Mediated Organic Reactions "
Kargbo, R. B. and Cook, G. R.
Current Organic Chemistry, 2007, 11, 1287.

2006

"Atom Transfer Cyclization Catalyzed by InCl3 via Halogen Activation"
Cook, Gregory R. and Hayashi, Ryuji
Org. Lett. 2006, 8, 1045.

"Tandem Palladium-Catalyzed Allene Arylation and Oxazoline Formation "
Cook, Gregory R. and Xu, Wei
Heterocycles 2006, 67, 215-232. Special Edition Honoring Prof. Trost

”2,2,6-Trimethyl-4H-1,3-dioxin-4-one”
Cook, G. R.; Hayashi, R.
Encyclopedia of Reagents for Organic Synthesis 2006, John Wiley & Sons, Ltd.

"Copper (II) Acetylacetonate”
Cook, G. R.; Hayashi, R.
Encyclopedia of Reagents for Organic Synthesis 2006, John Wiley & Sons, Ltd

2005

"Hydrogen Bond Directed Palladium-Catalyzed Allylic Substitution of Cyclic Substrates"
Cook, Gregory R.; Saraswathiamma, Manjusha
Tetrahedron Lett. 2005, 38, 6491.

"Three Carbon-Heteroatom Bond: Amides and Derivatives; Peptides; Lactams" Chapter 21.1.4 "Synthesis from Amines"
Cook, G. R.; Science of Synthesis, Vol 21, S. Weinreb, Ed.; 2005, Goerg Thieme Verlag KG, Stuttgart.

"Catalytic Enantioseletive Indium-Mediated Allylation of Hydrazones"
Cook, G. R.; Kargbo, R.; Maity, B.
Org. Lett., 2005, 7, 2767.

2004

"Synthesis and Evaluation of Novel Oxazoline MMP Inhibitors"
Cook, G. R., Manivannan, E. Underdahl, T.; Lukacova, V.; Zhang, Y.; Balaz, S.
Biorg. Med. Chem. Lett., 2004, 14, 4935.

"Nitrogen Heterocycles via Palladium-Catalyzed Carbocyclization. Formal Synthesis of (+)-a-Allokainic Acid "
Cook, G. R. and Sun, L.
Org. Lett., 2004, 6, 2481.

"Highly Diastereoselective Indium-Mediated Allylation of Chiral Hydrazones"
Cook, G. R.; Maity, B.; Kargbo, R.
Org. Lett., 2004, 6, 1741.

2003

"Hydrogen Bond Directed Highly Regioselective Palladium-Catalyzed Allylic Substitution"
Cook, G. R.; Yu, H.; Sankaranarayanan, S.; Shanker, P. S.
J. Am. Chem. Soc. 2003, 125, 5115.

2002

"Stereoselective Synthesis of D-erythro- and L-threo-Sphinganines via Palladium-Catalyzed Equilibration and Suzuki Coupling"
Gregory R. Cook and Ketheeswaran Pararajasingham
Tetrahedron Letters 2002, 43, 9027-9029.

2001

"Palladium-Mediated Regiodivergent Kinetic Resolution"
Cook, G. R.; S. Sankaranarayanan
Org. Lett. 2001, 3, 3531.

"Stereoselective Synthesis of MeBmt and (4R,5S)-2-Phenyl-4-(methoxycarbonyl)-5-isopropyloxazoline by a Pd-Catalyzed Equilibration"
Cook, G. R.; P. Sathya Shanker
J. Org. Chem. 2001, 66, 6818.

2000

"Transition Medal-Mediated Kinetic Resolution"
Cook, G. R.
Curr. Org. Chem. 2000 4, 883.

"Copper Lewis Acids in Organic Synthesis"
Sibi, M. P.; Cook, G. R.
in Handbook of Lewis Acids; Yamamoto, H., Ed., Wiley-VCH, 2000.

"Enantioselective Reduction of Ketones using Oxazaborolidines."
Sibi, M. P.; Liu, P.; Cook, G. R.
in Catalysts for the Fine Chemical Industry Roberts, S. M., Ed., Wiley, Oxford, 2000.

1999

"Asymmetric Synthesis of the Balanol Heterocycle via a Palladium-Mediated Epimerization and Olefin Metathesis"
Cook, G. R.; Shanker, P. S.; Peterson, S. L.
Org. Lett. 1999, 1, 615.

"Reversal of Stereochemistry in Diethylzinc Addition to Aldehydes by a Simple Change of the Backbone Substituent in L-Serine Derived Ligands"
Sibi, M. P.; Chen, J.-X.; Cook, G. R.
Tetrahedron Lett. 1999, 40, 3301.

"Enantioselective Reduction of Ketones. Examination of Bifunctional Ligands"
Sibi, M. P.; Cook, G. R.; Liu, P.
Tetrahedron Lett. 1999, 40, 2477.

"Palladium-Mediated Dynamic Kinetic Resolution. Stereoselective Synthesis of Vicinal Diamines"
Cook, G. R.; Shanker, P. S., Pararajasingham, K.
Angew. Chem., Int. Ed. Engl. 1999, 38, 110.

1998

"Chloride Effect on the Palladium-Catalyzred Allylic Substitution vs Elimination of Cyclic Vinyloxazolidinones and Oxazolines"
Cook, G. R.; Shanker, P. S.
Tetrahedron Lett. 1998, 39, 4991.

"Palladium-Catalyzed Formation and Stereoselective Isomerization of 5-Vinyloxazolines. Application to the Formal Synthesis of (S,S)-4-Amino-3-hydroxy-5-phenylpentanoic Acid"
Cook, G. R.; Shanker, P. S. Tetrahedron Lett. 1998, 39, 3405.

Publications prior to NDSU

"An Asymmetric Synthesis of (-)-Epibatidine"
Trost, B. M.; Cook, G. R.
Tetrahedron Lett. 1996, 37, 7485.

"Construction of Hydroxylated Alkaloids (±)-Mannonolactam, (±)-Deoxymannojirimycin, and (±)-Prosopinine through Aza-Annulation"
Cook, G. R.; Beholz, L. G.; Stille, J. R.
J. Org. Chem. 1994, 59, 3575.

"Aza-Annulation as a Route to Hydroxylated Alkaloid Lipids. The Synthesis of (±)-Prosopinine"
Cook, G. R.; Beholz, L. G.; Stille, J. R.
Tetrahedron Lett. 1994, 35, 1669.

"Stereochemical Consequences of the Lewis Acid-Promoted 3-Aza-Cope Rearrangement of N-Alkyl-N-allyl Enamines"
Cook, G. R.; Stille, J. R.
Tetrahedron 1994, 50, 4105.

"Studies of the Regiospecific 3-Aza-Cope Rearrangement Promoted by Electrophilic Reagents" Barta, N. S.; Cook, G. R.; Landis, M. S.; Stille, J. R.
J. Org. Chem. 1992, 57, 7188.

"Lewis Acid-Promoted 3-Aza-Cope Rearrangement of N-Alkyl-N-allylenamines"
Cook, G. R.; Barta, N. S.; Stille, J. R.
J. Org. Chem. 1992, 57, 461.

"Preparation and 3-Aza-Cope Rearrangement of N-Alkyl-N-allyl Enamines"
Cook, G. R.; Stille, J. R.
J. Org. 1991, 56, 5578.